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Advanced retinol serum with time release technology

8 Reviews

Advanced retinol serum with time release technology

8 Reviews


Looking to reduce the appearance of fine lines and wrinkles? Retinol is the gold standard in any anti-aging skin care regimen, and this powerful retinol serum has you covered, with a 0.75% pure retinol concentration.

The proprietary time-release technology minimizes irritation, while our signature ingredient, the European blueberry, in synergy with hydrating hyaluronic acid, jojoba, and collagen-boosting red clover, calms the skin and helps to minimize side effects typically associated with retinol.

A cocktail of powerful antioxidants including apple stem cell extract, edelweiss, and green tea, further enhances the skin's youthful appearance and defends against signs of aging caused by the sun.

  • 1 oz

    Visibly reduces the appearance of fine lines and wrinkles

    Visibly reduces the appearance of age spots


    Anti-aging benefits

  • Apply a pea-sized amount in the evening to clean, dry skin, on face and neck, avoiding the eye area, once or twice per week. Follow with a moisturizer if desired. For sensitive skin, begin using once per week to allow skin to acclimate and gradually work up to recommended frequency of use. Protect your results by wearing sunscreen daily.


    Flaking and redness may be possible. Do not use this product if you are nursing or pregnant. Avoid facial waxing for 72 hours pre and post application.


    0.75% retinol (pure retinol and retinol in time-release technology), hyaluronic acid, vitamin C, vitamin E, green tea (catechin, quercetin, epicatechin), European blueberry (anthocyans, quercetin, resveratrol), edelweiss, red clover (isoflavone), apple (phloretin), jojoba.


    Water/Aqua, Caprylic/Capric Triglyceride, Isononyl Isononanoate, Glycerin, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Allyl Methacrylates Crosspolymer, Squalane, Simmondsia Chinensis (Jojoba) Seed Oil, Retinol, Camellia Sinensis (Green Tea) Leaf Extract, Vaccinium Myrtillus (Bilberry) Fruit Extract, Leontopodium Alpinum (Edelweiss) Extract, Trifolium Pratense (Clover) Flower Extract, Malus Domestica Fruit Cell Culture Extract, Sodium Hyaluronate, Ascorbyl Glucoside, Tocopherol, Polysorbate 20, Polysorbate 60, Sodium Hydroxide, Sodium Metabisulfite, Isomalt, Disodium EDTA, Chlorphenesin, Benzyl Alcohol, Benzoic Acid, Sorbic Acid, Fragrance/Parfum, Geraniol, Hexyl Cinnamal, Alpha Isomethyl Ionone, Amyl Cinnamal, Linalool, Butylphenyl Methylpropional, Citronellol, Limonene

    Visit our Full Ingredient List and Definition page to learn more about our ingredients. 


    Parabens, sulfates, mineral oil, silicones, propylene glycol, ethoxylated ingredients (PEGs), phenoxyethanol, gluten, dyes, phthalates, genetically-modified organisms (GMOs), formaldehyde and formaldehyde releasers, soy, nuts, animal testing, animal byproducts.

  • Learn more about our New! Advanced Retinol Serum.


  • Our Recent Press:

Clean formulations, clinical results. Dermatologist-formulated and tested. Paraben-free, gluten-free, cruelty-free and vegan.

Customer Reviews
4.4 Based on 8 Reviews
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Filter Reviews:
Christine v.
Switzerland Switzerland
Advanced Retinol 0.75 Serum with time release technology

Used that serum once a week / ( tried twice a week, but the skin reaction was too strong ! ) < The RESULT is better than the one obtained with "Fraxel Laser Dual" as far as the surface of the skin is concerned. < Fraxel Laser Dual acts more deeply in the dermal tissues but its results are far less noticeable on the skin surface ( wrinkles ) smoothness of the skin, glow. < I'm puzzled by Advanced Retinol 0.75% Serum effects. / ..... didn't start with retinol 0.2, 0.3, 0.5 and haven't tried Retinol 1.0 Thank you Alchimie-Forever

Abigail P.
United States
So far so good

I have really dry and sensitive skin, so I was a bit tenative about trying a retinoid. I've buffered it with the Calming Cream and although I've had dry patches, it's been tolerable. I'm still only using this once a week and will slowly build up to either no buffering or two times a week. I would recommend. High quality!

Dena M.
United States
Great Results

I stopped using retinol based products for several months and noticed my fine lines were showing up again. Decided to try Alchimie and within two applications I saw the difference in my skin. The fine lines and wrinkles were less prominent and the overall appearance of my skin was healthier and more radiant. I didn't experience any irritation from the retinol and not only will reorder this product, but enjoyed the free samples and will be trying some other products as well.

A Alchimie Forever Customer
Kassandra R.
United States
Skin Happy and Wrinkle Free

OK - My skin isn’t wrinkle free, but rather less wrinkly. :-) Been using once a week and no peeling. Yay! Going to increase to 2x/week. Love that is feels lighter than other retinol lotions I’ve tried!! I think it’s because yours is a serum, vs a lotion, which I love.

Excellent product

I've been using this serum since it launched, and my skin looks more firm, more even, and fine lines and wrinkles are less noticeable. It is light and absorbs quickly. I did have mild redness and flaking the first few weeks of use, but it was barely noticeable and stopped after the initial adjustment period. I've been very happy with the results so far, and can't wait to see how my skin continues to improve in the coming months.